Buffalo is a city in western New York state and the county seat of Erie County, on the eastern shores of Lake Erie at the head of the Niagara River.
Lake Erie is the fourth-largest lake of the five Great Lakes in North America, and the thirteenth-largest globally if measured in terms of surface area.
A county seat is an administrative center, or seat of government, for a county or civil parish.
The Niagara River is a river that flows north from Lake Erie to Lake Ontario.
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As of 2014, Buffalo is New York state's 2nd-most populous city after New York City, with 258,703 residents.
The City of New York, often called New York City, New York, or simply The City, is the most populous city in the United States.
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The metropolitan area has a population of 1.13 million.
Buffalo grew significantly in the 19th and 20th centuries as a result of the Erie Canal, railroads and Lake Erie, providing an abundance of fresh water and an ample trade route to the midwestern United States, while grooming its economy for the grain, steel and automobile industries during the 20th century.
The Midwestern United States, also referred to as the American Midwest or simply the Midwest, is one of the four geographic regions defined by the United States Census Bureau, occupying the northern central part of the United States of America.
The Erie Canal is a canal in New York that is part of the east-west, cross-state route of the New York State Canal System.
After an economic downturn in the latter half of the 20th century, Buffalo's economy has transitioned to sectors that include financial services, technology, biomedical engineering and education.
Biomedical engineering is the application of engineering principles and design concepts to medicine and biology for healthcare purposes.
Residents of Buffalo are called "Buffalonians".
The city's nicknames include "The Queen City", "The Nickel City", and "The City of Good Neighbors".